Home   >   Medicine   >   Skin and Hair
Epidermolysis Treatment

Persons with mild forms of Epidermolysis Bullosa (EB) may not require extensive treatment. However, they should attempt to keep blisters from forming and prevent infection when blisters occur. Individuals with moderate and severe forms may have many complications and require psychological support along with attention to the care and protection of the skin and soft tissues.

Preventing Blisters

To protect the skin from forming blisters, you can:

  • Avoid getting too hot by keeping rooms at an even temperature
  • Apply lotion to the skin to reduce friction and keep the skin moist
  • Wear soft clothing
  • Use sheepskin on car seats and other hard surfaces
  • Wear mittens at bedtime to help prevent scratching.

Treating Blisters

When blisters appear, the goal of care is to:

  • Reduce pain or discomfort
  • Prevent loss of body fluid
  • Promote healing
  • Prevent infection.

Doctors may treat the blisters by:

  • Explaining how to safely break a blister in its early stages
  • Prescribing a mild painkiller so that changing bandages won't hurt as much
  • Recommending special bandages that will help the blisters to heal, lessen the pain, and prevent infection.

Treating Infection

The chances of skin infection can be reduced by good nutrition, which builds the body's defenses and promotes healing, and by careful skin care with clean hands and use of sterile materials. For added protection, the doctor may recommend antibiotic ointments and soaks.

Even in the presence of good care, it is possible for infection to develop. Signs of infection are redness and heat around an open area of skin, pus or a yellow drainage, excessive crusting on the wound surface, a red line or streak under the skin that spreads away from the blistered area, a wound that does not heal, and/or fever or chills. The doctor may prescribe a specific soaking solution, an antibiotic ointment, or an oral antibiotic to reduce the growth of bacteria. Wounds that are not healing may be treated by a special wound covering or biologically developed skin.

Treating Nutritional Problems

Blisters that form in the mouth and esophagus in some people with EB are likely to cause difficulty in chewing and swallowing food and drinks. If breast or bottle feeding results in blisters, infants may be fed using a preemie nipple (a soft nipple with large holes), a cleft palate nipple, an eyedropper, or a syringe. When the baby is old enough to take in food, adding extra liquid to pureed (finely mashed) food makes it easier to swallow. Soups, milk drinks, mashed potatoes, custards, and puddings can be given to young children. However, food should never be served too hot.

Dietitians are important members of the health care team that assists people with EB. They can work with family members and older patients to find recipes and prepare food that is nutritious and easy to consume. For example, they can identify high-caloric and protein-fortified foods and beverages that help replace protein lost in the fluid from draining blisters. They can suggest vitamin and mineral nutritional supplements that may be needed, and show how to mix these into the food and drinks of young children. Dietitians can also recommend adjustments in the diet to prevent gastrointestinal problems, such as constipation, diarrhea, or painful elimination.

Surgery

Surgical treatment may be necessary in some forms of EB. Individuals with the severe forms of autosomal recessive Dystrophic EB whose esophagus has been narrowed by scarring may require dilation of their esophagus for food to travel from the mouth to the stomach. Other individuals who are not getting proper nutrition may need a feeding tube that permits delivery of food directly to the stomach. Also, patients whose fingers or toes are fused together may require surgery to release them.

 

Reference:

National Institute of Arthritis and Musculoskeletal and Skin Diseases, USA.