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47. p53 Tumor Suppressor Protein Triggers Cell Suicide

p53 Tumor Suppressor Protein Triggers Cell Suicide

 

One particular tumor suppressor gene codes for a protein called "p53" that can trigger cell suicide (apoptosis). In cells that have undergone DNA damage, the p53 protein acts like a brake pedal to halt cell growth and division. If the damage cannot be repaired, the p53 protein eventually initiates cell suicide, thereby preventing the genetically damaged cell from growing out of control.

 

Source:

National Cancer Institute, USA.