MoBio DNA Recombination Chapter 8

DNA recombination refers to the process that a DNA segment moves from one DNA molecule to another DNA molecule. The following three types are the most commonly observed.

Homologous recombination
It occurs between two homologous DNA molecules, also called DNA crossover.

Site-specific recombination
It occurs at a specific DNA sequence which is present in both non-homologous DNA molecules that may have the recombination.

Transpositional recombination
A mobile element is inserted into a target DNA.


The homologous recombination often occurs during meiosis. Other types of recombination are not specifically related to cell division.