Signaling enzymes which are cell-surface receptors:
Receptor tyrosine kinases
Receptor serine/threonine kinases
Receptor tyrosine phosphatase
-- catalyze the dephosphorylation of the tyrosine residue.
Review Articles - European J. Biochem., 2002
Structure
and function of protein phosphatases
Receptor guanylyl cyclase
-- catalyze the synthesis of cGMP
-- Example: natriuretic peptide receptor (Review)
Signaling enzymes anchored on the cytosolic face of the plasma membrane:
Non-receptor tyrosine kinases
Ras
Review Articles:
Innate Sensing of
Viruses by Toll-Like Receptors - J. Virology, 2004.
A genomic
perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and
genetic disease linkage - FASEB J., 2004.
Toll-like
Receptor Signaling - J. Biol. Chem., 2003.
Differential
Adapter Utilization by Toll-Like Receptors Mediates TLR-Specific Patterns of
Gene Expression - Mole. Interv., 2003.
Toll-Like
Receptors in Health and Disease: Complex Questions Remain - J. Immuno.,
2003.
Reciprocal
regulation of lymphocyte activation by tyrosine kinases and phosphatases
- J. Clinical Investigation, 2002.
Structural
and Evolutionary Relationships among Protein Tyrosine Phosphatase Domains
- Molecular and Cellular Biology, 2001.
Protein-protein
interactions define specificity in signal transduction - Genes
and Development, 2000.
|