Figure 6-D-1. Signaling via
(a) Before agonist binding to the
G-protein-coupled receptor, the three subunits of a G protein are bound
(b) The agonist binding causes interaction between the
G-protein-coupled receptor and the G protein.
(c) Their interaction results in the dissociation between α and βγ
subunits of the G protein. The separated α and/or βγ
subunits may then interact with effectors.