MoBio Signaling via G-protein-Coupled Receptors Chapter 6

Figure 6-D-1. Signaling via G-protein-coupled receptors.
(a) Before agonist binding to the G-protein-coupled receptor, the three subunits of a G protein are bound together.
(b) The agonist binding causes interaction between the G-protein-coupled receptor and the G protein.
(c) Their interaction results in the dissociation between α and βγ subunits of the G protein. The separated α and/or βγ subunits may then interact with effectors.