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mRNA and DNA

 


mRNA is transcribed from DNA, carrying information for protein synthesis.  Three consecutive nucleotides in mRNA encode an amino acid or a stop signal for protein synthesis (see Genetic Code).  The trinucleotide is know as a codon.

Figure 3-E-3.  The sequence relationship of DNA, mRNA and the encoded peptide .  The sequence of mRNA is complementary to DNA's template strand, and thus the same as DNA's coding strand, except that T is replaced by U.


Review Article:

Curbing the nonsense: the activation and regulation of mRNA surveillance - Genes and Development, 2001.