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Cellular Nucleotides and Nucleosides

 


In cells, a free nucleotide may contain one, two or three phosphate groups.  The energy carrier ATP (adenosine triphosphate) has three phosphate groups; ADP (adenosine diphosphate) has two; AMP (adenosine monophosphate) has one.  Their structures are shown in the following figure.

Figure 3-A-4.  (a) A computer model of AMP.  (b) Chemical structures of Adenosine, ADP and ATP.  They differ in the number of phosphate groups.

 

If all phosphate groups are removed, a nucleotide becomes a nucleoside such as adenosine.  The following table lists various nucleosides and nucleotides.

   Table 3-A-1.  Cellular nucleosides and nucleotides.

NMP = nucleoside monophosphate
NDP = nucleoside diphosphate
NTP = nucleoside triphosphate
dNMP = deoxynucleoside monophosphate
dNDP = deoxynucleoside diphosphate
dNTP = deoxynucleoside triphosphate

(nucleoside = ribonucleoside; deoxynucleoside = deoxyribonucleoside)