MoBio Membrane Attached Proteins Chapter 2

Membrane-attached proteins can be divided into three groups:

  • bound to the cytosolic face of the plasma membrane by myristate;
  • bound to the cytosolic face of the plasma membrane by farnesyl;
  • bound to the extracelluar face of the plasma membrane by glycosylphosphatidylinositol.
Image

Figure 2-F-7. Illustration of anchors by which some proteins are bound to the plasma membrane. v-Src is a kind of non-receptor protein tyrosine kinase involved in cell signaling. Ras protein also plays a key role in cell signaling (Chapter 6 Section E).