Membrane-attached proteins can be divided into three groups:
- bound to the cytosolic face of the plasma membrane by myristate;
- bound to the cytosolic face of the plasma membrane by farnesyl;
- bound to the extracelluar face of the plasma membrane by glycosylphosphatidylinositol.
Figure 2-F-7. Illustration of anchors by which some
proteins are bound to the plasma membrane. v-Src is a kind of non-receptor protein
tyrosine kinase involved in cell signaling. Ras protein also plays a key role in cell
signaling (Chapter 6 Section E).